Evaluation of the Multimycotoxin-Degrading Efficiency of Rhodococcus erythropolis NI1 Strain with the Three-Step Zebrafish Microinjection Method

The multimycotoxin-degrading efficiency of the Rhodococcus erythropolis NI1 strain was investigated with a previously developed three-step method. bacterial metabolites, single and combined mycotoxins their degradation products, were injected into one cell stage zebrafish embryos in same doses. Toxic interaction effects supplemented UHPLC-MS/MS measurement toxin concentrations. Results showed that able to degrade mixtures different proportions, where higher ratio reduced combination than ones. toxic mixtures, except for AFB1+T-2 mixture. Degradation products mixture by more initial mixture, while analytical results very high degradation, which means degraded this products. detoxify AFB1, ZEN, T-2 toxins (except mixture) during experiments, these non-toxic demonstrate exposures toxic. exposure had synergistic effects, ZEN+T-2 AFB1+ZEN +T-2, whose strong antagonistic effects.